Why anti-inflammatory drugs irritate the stomach
Aspirin, ibuprofen, and other NSAIDs are commonly used for headaches, fever, arthritis, and muscle pain. However, their mechanism of action can irritate the gastric mucosa, causing even significant damage.
The most common side effects include:
- indigestion and heartburn
- increased blood pressure
- increased risk of heart attack and stroke
- possible kidney damage and worsening of asthma
Risks increased by drug combinations
Dr. Porter stressed that the risks increase with high dosages or prolonged use:
- Those who take NSAIDs are approximately four times more likely to develop gastric bleeding than those who do not use them.
- the association with SSRI antidepressants can increase the risk up to 7 times
- combining it with steroids can increase it up to 12 times
Doctor’s advice to reduce risks
To limit the damage, Porter recommends combining NSAIDs with gastric protector drugs such as omeprazole or lansoprazole, which reduce stomach irritation.
For self-medication, he also suggests preferring paracetamol to ibuprofen or aspirin:
“It may not be effective for everyone, but it is much safer, unless you exceed the recommended doses.”
A further recommendation concerns the combined use of drugs: those already taking an NSAID should avoid aspirin, as it further increases the risk of ulcers and bleeding due to its effect on clotting.
Conclusion
Anti-inflammatory drugs are widespread and useful, but they are not without risks. Dr. Porter’s warning urges caution: avoid overuse, don’t combine medications without medical advice, and protect your stomach when necessary ️️ Continue on the next page ️️
